Radiofrequency ablation as bridging strategy for liver transplantation

Quality Ablation with CAS-One IR enabled to provide the patient with ablation as a tissue sparing treatment option. Moreover the intervention fostered to stop growth and further spread of the tumour to adjecent organs or vessels. This allowed to continue the treatment strategy and keep the patient on the waiting list for liver transplant surgery. 

   
Case_Overview_Cambridge
  
Row 1: Segmented image of the lesion (left) and planning of overlapping ablation zone (right)
Row 2: Validation of needle position after placement
Row 3: Assessment of the ablation zone using AblaSure (axial view)
Row 4: Assessment of the ablation zone using AblaSure (MPR view)

Name: Dr. Nadeem Shaida 


Institution: Addenbrooke's Hospital, Cambridge (UK)


Patient age and sex: 60 years, male


Initial condition:

  • Patient weight: 116 kg
  • Patient has a history of smoking and alcohol consumption
  • Diagnosed with Liver cirrhosis, COPD and type two diabetes
  • 44mm HCC lesion in Liver Segment VI diagnosed in May 2020
  • Multiple Hepatic TAE performed In Aug 2020, Nov 2020 and Jan 2021. Unsuccessful and resulted in relapse
  • The now 3.9mm Tumour in segment V/VI of the Liver to be treated with Ablation Therapy
  • Additionally, the patient is awaiting assessment for liver transplant surgery
  • Ablation is planned with the aim to prevent growth and spread of the tumour prior to transplant

Treatment: 

  • 3 Needle RFA treatment planned with overlapping ablation zones
  • Freehand, percutaneous ablation would not be a viable treatment option due to the large size of the lesion and the difficulty in planning overlapping treatments
  • Treatment with CAS-One IR allowed for safe and precise planning and treatment of this large lesion with the use of three overlapping ablation zones
  • Post ablation verification of the treatment was done using AblaSure for quantitative margin assessment

Result:

  • The current oncological strategy can be continued
  • Quality Ablation with CAS-One IR enabled to provide the patient with ablation as a tissue sparing treatment option for this large lesion
  • The successful outcome of the treatment will prevent growth and spread of the tumour, improving the prospects for undergoing transplant surgery with the aim to improve long term survival

Learn more about the stereotactic navigation system CAS-One IR.

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