Quality Ablation with CAS-One® IR
Reproducible and Standardized Tumour Treatments

Quality Ablation in 144 seconds

Watch the video and learn how Quality Ablation with CAS-One IR contributes to treating more patients with challenging cases and helps achive consistently low complications, and recurrence rates. 

Quality Ablation in Liver, Lung, Kidney, Bone and Pancreas

Important Benefits of Quality Ablation with CAS-One IR

Tumor locations-1

Enhanced Reliability and Accuracy with CT/MRI Planning and Navigation

  • Plan and navigate treatment intuitively in 2D and 3D
  • Treat 'invisible lesions' through MRI fusion1
  • Visualize ablation volumes of >75 MW, RFA, Cryo, IRE devices2
  • Improve accuracy through mechanical needle guidance3,4
  • Achieve low repositioning rates (1%)5

more patients-1

Treating more Patients with Challenging Cases

  • Maintain confidence near structures of risk with ablation planning and navigated needle placement
  • Treat multiple and/or large tumours (> 3cm) with overlapping ablation zones6,7
  • Increase ease of complex cases with angulation, long distance to target7
  • Reduce intervention time by 57% and variability by 67% enabling treatment of more patients4

Tumor locations

Consistently Low Complications,
and Reduced Recurrence Rates

  • Reduce recurrence rates8 (9% vs. 14-30%) with safe and reliable ablations
  • Achieve low overall complication rates (6%)7
  • Add consistency to treatment success with ablation validation10
  • Reduce bleeding and tumour seeding5 with low needle repositioning rate (1%)
4500

Quality Ablation Treatments

26

Quality Ablation Centers

12

Quality Ablation Countries

Quality Ablation with CAS-One IR - A Unique Process


1 Image

51 image
  • CT imaging
  • MRI fusion

2 Plan

52 plan
  • 2D/3D planning of trajectories
  • Single/Multiple needles
  • Tumour & margin visualisation
  • Simulation of ablation volumes

3 Navigate

53 navigate
  • Guided needle placement

4 Double-Check

54 double check
  • Verification of needle position
  • Update simulation of ablation volume

5 Treat

55 treat
  • Microwave ablation
  • Radiofrequency ablation
  • Irreversible Electroporation
  • Cryoablation
  • Biopsy

6 Confirm

56 confirm
  • Verification of ablation volume
  • Verification of safety margins
  • Treatment documentation
cas one zoom 02b

Enhanced Reliability & Accuracy with CT/MRI Planning & Navigation

  • Plan and navigate treatment intuitively in 2D and 3D
  • Treat 'invisible lesions' through MRI fusion1
  • Visualize ablation volumes of >75 MW, RFA, Cryo, IRE devices2
  • Improve accuracy through mechanical needle guidance3,4
  • Achieve low repositioning rates (1%) 5

Treating More Patients with Challenging Cases

5regions1 copy@2x-8
5regions2 copy@2x-8
  • Increase ease of complex cases with high angulation, long distance to target7
  • Limit needle repositioning need with low repositioning rate (1%) 5
  • Maintain confidence near structures of risk with ablation planning and navigated needle placement
  • Possibility to treat multiple and/or large tumours
    (>3 cm) with overlapping ablation zones6,7 

Consistently Lower Recurrence Rates and Complications

  • Significantly reduce recurrence rates8 (9% vs 14-30%) with safe and reliable ablations
  • Low overall complication rates (6%) 7
  • Add consistency to treatment success with ablation validation9
  • Reduce bleeding and tumour seeding5 with low needle repositioning rate (1%)
Low Recurrence Rates1
An important indicator of efficacy in the treatment of tumours in the liver is the local recurrence rate. A study covering 1,000 lesions shows that computer-assisted ablation of tumours based on CT-imaging and Quality Ablation with CAS-One IR is a reliable and highly effective treatment. It can improve patient outcomes by lowering the local recurrence rate compared to other imaging modalities8.

Quality Ablation reduces Treatment Time

Standardising procedure planning accelerates treatment by reducing needle placement time and need to repositioning

Conventional IRE

Conventional IRE

Stereotactic IRE  CAS-One IR

Stereotactic IRE CAS-ONE IR

     Preparation         Planning          Needle Placement

Reduce intervention time by 57% and variability by 67% enabling treatment of more patients.4

Reduction of Radiation Dose

Standardised Quality Ablation workflow leads to lower exposure to radiation dose

The more scans you do, the higher the radiation dose both for patients and physicians. With lesions easily accessible, this is not a problem. But the more advanced treatments you're doing with double angulated trajectories or multiple needles the complexity increases. The same is true for the radiation dose, because complex treatments usually require more scans. The workflow of Quality Ablation standardises treatment time also in complex cases. The result is a significant reduction in radiation dose.

The Quality Ablation experience

This 13-minute video, filmed during a real intervention, guides you through the six steps of each Quality Ablation procedure: Imaging, planning, navigation, validation, treatment and treatment verification. It provides in depth insights on why standardisation is key to obtaining improved outcomes for patients.

Quality Ablation
Success Stories


Learn how the start of a Quality Ablation program helps to expand treatment options for tumour patients.

5Blog

CASCINATION Cases

Quality Ablation Blog

With their clinical cases our experts showcase the benefits of tumour treatment with CAS-One IR.

CASCINATION Webinar

June 14, 6:00 pm CET

Combining Technologies in Interventional Oncology

Understanding the value of the NanoKnife 3.0 System and CAS-One IR with speakers:

Dr. Hester Scheffer, Radiology Resident Amsterdam UMC, Amsterdam (Netherlands)
Prof. Dr. Tze Min Wah, Senior Consultant Interventional Radiology St. James Hospital, Leeds (United Kingdom)

Quant - Quality Ablation Training Phantom

phantom-composite-01

References

1. Cathomas, M., Mertineit, N., Kim-Fuchs, C. et al. Value of MRI/CT Image Fusion for Targeting “invisible” Lesions in Stereotactic Microwave Ablation (SMWA) of Malignant Liver Lesions: A Retrospective Analysis. Cardiovasc Intervent Radiol 431505–1514 (2020).
2. CAS-One IR Software Release 3.1.3
3. Wallach D, Toporek G, Weber S, Bale R, Widmann G. Comparison of freehand-navigated and aiming device-navigated targeting of liver lesions. Int J Med Robot. 2014 Mar;10(1):35-43.
4. Beyer LP, Pregler B, Nießen C, Schicho A, Haimerl M, Jung EM, Stroszczynski C, Wiggermann P. Stereotactically-navigated percutaneous Irreversible Electroporation (IRE) compared to conventional IRE: a prospective trial. PeerJ. 2016 Aug 11;4:e2277
5. Tinguely P, Frehner L, Lachenmayer A, Banz V, Weber S, Candinas D and Maurer MH (2020) Stereotactic Image-Guided Microwave Ablation for Malignant Liver Tumors—A Multivariable Accuracy and Efficacy Analysis. Front. Oncol. 10:842.
6. Schullian, P. et al. Safety and efficacy of stereotactic radiofrequency ablation for very large (≥8 cm) primary and metastatic liver tumors. Sci. Rep. 10, 1618 (2020)
7. Lachenmayer A, Tinguely P, Maurer MH, Frehner L, Knöpfli M, Peterhans M, Weber S, Dufour JF, Candinas D, Banz V. Stereotactic image-guided microwave ablation of hepatocellular carcinoma using a computer-assisted navigation system. Liver Int. 2019
8. Beermann, M. et al. (2019). 1000 consecutive ablation sessions in the era of computer assisted image guidance - Lessens learned. Eruo J Rad 0, 6 (October 2018), 1-8.
9. Laimer G, Schullian P, Jaschke N, Putzer D, Eberle G, Alzaga A, Odisio B, Bale R. Minimal ablative margin (MAM) assessment with image fusion: an independent predictor for local tumor progression in hepatocellular carcinoma after stereotactic radiofrequency ablation. Eur Radiol. 2020 May;30(5):2463-2472.

Where to find Quality Ablation

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