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Quality Ablation
with CAS-One®  IR
Reproducible and Standardised Tumour Treatments

10624

Quality Ablation Treatments

70

Quality Ablation Centers

21

Quality Ablation Countries


Quality Ablation with Dr. Nadeem Shaida

Watch the video and learn how Quality Ablation with CAS-One IR contributes to treating more patients with challenging cases and helps achieve consistently low complications, and recurrence rates.

Dr. Nadeem Shaida has been using CAS-One IR for several years and explains the impact it has on his patients and his hospital.

Benefits of Quality Ablation with CAS-One IR

Tumor locations

Reduce Local Tumor Progression and Complications 

  • Reduce LTP from 14-30% to 8-9%1-2
  • Achieve fewer complications and with lower severity with same OS3
  • Reduce bleeding and tumor seeding with low needle repositioning (1%)4
  • Evaluate treatment success immediately with AblaSure
  • Consistent results with multiple operators1

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Treat More Complex Cases

  • Plan and navigate treatment in 2D and 3D with AI-driven visualizations
  • Visualize ablation volumes with over 75 needles across all modalities
  • Treat all segments of the liver regardless of proximity to critical structures with consistent success4,5
  • Facilitate long, double angulated trajectories6
  • Treat multiple or large (>3cm) tumors with overlapping ablation zones3,4,7,8
  • Treat lesions invisible of US/CT with MRI fusion9

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Maximize Hospital Resources

  • Reduce intervention time by 57% and variability by 67%10, freeing CT room time
  • Reduce radiation by 30-50%5,10
  • Total cost reduced by 1/3rd compared to surgery11


Tumor Ablation with
CAS-One IR - Full Procedure

This 16-minute video, filmed during a real intervention, guides you through the four steps of each Quality Ablation procedure: Plan, Place, Verify and Assess. It provides in depth insights on why standardization is key to obtaining improved outcomes for patients.

Quality Ablation with CAS-One IR - A Unique Process


1 Plan

52 plan
  • Single and multi-instrument trajectories
  • Tumours
  • Safety margins
  • Ablation volumes(from manufacturer data)
  • Fuse CT / CT and CT / MRI

2 Place

53 navigate
  • Through semi-robotic guide

3 Verify

54 double check
  • Instrument position 
  • Re-plan if required

4 Assess

56 confirm
  • Effective ablation volume
  • Safety margins
  • Necessity of re-ablation
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Enhanced Reliability & Accuracy with CT/MRI Planning & Navigation

  • Plan and navigate treatment intuitively in 2D and 3D
  • Treat 'invisible lesions' through MRI fusion9
  • Visualize ablation volumes of >75 MW, RFA, Cryo, IRE devices
  • Improve accuracy through mechanical needle guidance10,12
  • Achieve low repositioning rates (1%) 6

Treating More Patients with Challenging Cases

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  • Increase ease of complex cases with high angulation, long distance to target4
  • Limit needle repositioning need with low repositioning rate (1%) 6
  • Maintain confidence near structures of risk with ablation planning and navigated needle placement
  • Possibility to treat multiple and/or large tumours
    (>3 cm) with overlapping ablation zones3,4,7,8 

A complete overview of the most recent CAS-One IR software

4.1 Driven by AI
Confidence in executing complex cases has never been easier.

Consistently Lower Recurrence Rates and Complications

  • Significantly reduce recurrence rates1-2 (9% vs 14-30%) with safe and reliable ablations
  • Low and reduced overall complication rates (6%) 3,4
  • Add consistency to treatment success with ablation validation13
Low Recurrence Rates1
An important indicator of efficacy in the treatment of tumours in the liver is the local recurrence rate. A study covering 1,000 lesions shows that computer-assisted ablation of tumours based on CT-imaging and Quality Ablation with CAS-One IR is a reliable and highly effective treatment. It can improve patient outcomes by lowering the local recurrence rate compared to other imaging modalities1.

Quality Ablation reduces Treatment Time

Standardising procedure planning accelerates treatment by reducing needle placement time and need to repositioning.

Conventional IRE

Conventional IRE

Stereotactic IRE  CAS-One IR

Stereotactic IRE CAS-ONE IR

     Preparation         Planning          Needle Placement

Reduce intervention time by 57% and variability by 67% enabling treatment of more patients.10

Reduction of Radiation Dose

Standardised Quality Ablation workflow leads to lower exposure to radiation dose5

The more scans you do, the higher the radiation dose both for patients and physicians. With lesions easily accessible, this is not a problem. But the more advanced treatments you're doing with double angulated trajectories or multiple needles the complexity increases. The same is true for the radiation dose, because complex treatments usually require more scans. The workflow of Quality Ablation standardises treatment time also in complex cases. The result is a significant reduction in radiation dose.

Where to find Quality Ablation Centers

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  • CASCINATION
  • Customer
  • Distributor
Quality Ablation with CAS-One IR - Brochure small

Download the new Quality Ablation with CAS-One IR brochure 

  • Clinical and economic benefits of Quality Ablation
  • The Quality Ablation workflow
  • Our service offerings

Quality Ablation Success Stories

Learn how the start of a Quality Ablation program helps to expand treatment options for tumour patients.

 

Prof. Dr. Martin Maurer

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CAS-One IR has helped us to be more precise in our work. And with ablations, great precision leads to better results.

Read the interview

Dr. Carlo Mario Stefano Tappero

f4

The increased safety during the intervention is an important benefit for the patients.

Read the interview

Dr. Marie Beermann & Prof. Dr. Jacob Freedman

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The cost of an ablation is a fourth of the cost of a resection. With five patients converted from surgery to ablation, the system has paid for itself.

Read the interview

Dr. Nadeem Shaida

f3

With AblaSure® you’ve got the absolute certainty, that you got your margins right.

Read the interview

Tumor Ablation in Liver, Lung, Kidney, Bone and Pancreas

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liver with segments@4x-1
Kidney@4x
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Quant - Quality Ablation Training Phantom

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Tumor Ablation Cases 

With their clinical cases our experts showcase the benefits of tumour treatment with CAS-One IR.
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Let’s get connected

Our Quality Ablation newsletter offers you the latest news about minimally invasive tumour treatments with CAS-One IR.

References

1.Beermann, M., et al.: 1000 consecutive ablation sessions in the era of computer assisted image guidance, Euro J Rad O 2018
2.Chapelle, T, op de Beeck, B, Bracke, B, Data presented at Angiodynamics Symposium Rome 2024
3.Tinguely et. Al, A prospective multicentre trial on survival after Microwave Ablation VErsus Resection for Resectable Colorectal liver metastases (MAVERRIC) Euro J Cancer 2023
4.Lachenmayer et al.: Stereotactic image-guided microwave ablation of hepatocellular carcinoma, Liver Int. 2019
5.Schaible, J. et. al., Primary efficacy of percutaneous microwave ablation of malignant liver tumors: comparison of stereotactic and conventional manual guidance. Scientific Reports 2020
6.Tinguely P et al.: Stereotactic Image-Guided Microwave Ablation for Malignant Liver Tumors, Front. Oncol 2020
7.Schullian, P. et al.: Safety and efficacy of stereotactic radiofrequency ablation for very large (≥8 cm) primary and metastatic liver tumors. Sci. Rep. 2020
8.Luerken, L et al, Stereotactic Percutaneous Electrochemotherapy as Primary Approach for Unresectable Large HCC at the Hepatic Hilum, CIRSE Case Reports, 2021
9.Cathomas et al.: Value of MRI/CT Image Fusion for Targeting “invisible” Lesions Cardiovasc Intervent Radiol 2020
10.Beyer LP et al.: Stereotactically-navigated IRE compared to conventional IRE, PeerJ 2016
11.Tinguely, P et al. Ablation versus resection for resectable colorectal liver metastases - Health care related cost and survival analyses from a quasi-randomised study Euro Journal Surg Onc. 2022
12. Wallach, et. al. Comparison of freehand-navigated and aiming-device navigated targeting of liver lesions, Int. Jour. Med. Robotics 2013
13. Laimer G, et. al. Minimal ablative margin (MAM) assessment with image fusion: an independent predictor for local tumor progression in hepatocellular carcinoma after stereotactic radiofrequency ablation. Eur Radiol. 2020 

Approved software versions differ per geography. Contact CASCINATION for details on which software is approved in your region.