CAS-One IR at The Grange University Hospital

Yr wythnos diwethaf – daeth CAS-One IR i Gymru!

For those not fluent in Welsh, last week, CAS-One IR was installed and used in Wales, at The Grange University Hospital.

The team first became interested in Quality Ablation this March (yes March 2025, and now they have it 6 months later). The interest came largely because of the COLLISION study - you can read our detailed blog post on that here. 

COLLISION was finally high-level evidence proving ablation to be non-inferior to surgery. The Oncologists noticed the research and delivered the results of the study back to the MDT to gain support from the IR and surgical consultants, pushing their passionate support for ablations. With the surgeons coming around to the idea, more and more patients were being referred to the IR team. With this newfound increase of patients, the team sought out CAS-One IR to ensure they could navigate difficult to reach lesions, ensure a complete treatment was achieved as well as being able to treat lesions invisible on CT, all whilst remaining time efficient. 

As a centre they already treat liver, lung and kidney lesions and have ambitions to use CAS-One IR for all.

The economic analysis began quickly and intensely, as like anywhere around the world, an airtight economic analysis must be completed. After much review, the go-ahead was given by the hospital management, and a CAS-One IR shipped, and training commenced. The first case went very smoothly and finished just over an hour, utilising the re-ablate workflow - it highlighted AblaSure quite nicely – with 100% of the tumor and 98% of the lesion covered (on an 8mm margin)

Shortly after – the second patient was scanned – and the lesions were not visible on CT. This was a surprise, but the team were ready to fuse the CT with an MRI from a month prior and fully treat the lesion. Without this ability to fuse CT/MRI, treating this patient would’ve been very challenging, and the patient would most likely have been woken up without having received the planned treatment.

Both of these patients would not have been fit enough for surgery and were pleased to be discharged same day from hospital.

Dr. Chris Chick describes the first cases:

"I'd have given the first case a crack as we think it was visible on US, but we wouldn't have had a chance on the second case. It is a radical game changer for the treatment we can offer at Grange University Hospital"

Dr. Nimit Goyal was also impressed:

"What can I say - there were lots of headline features & benefits to the CAS-One device, but it wasn't until I saw it in action on Wednesday that I was sold on the difference it can make to the GUH practice. We are committed to pushing the boundaries of what is possible, and we are incredibly happy to have the device onsite"

 Dr. Chris Williams said of the first cases:

"CAS-One IR has so many features we used in the first cases that positively impacted the outcome of the ablations - it is truly a Swiss Army knife"

                                AI-Driven AblaSure of one of the first patients, showing excellent coverage of the tumor and margin

We at CASCINATION can't thank the team enough for putting in the work to not only convince their hospital to acquire CAS-One IR, but also in their effort towards training prior to the first list. This always adds to the short and long-term success.